Amasomo n’Enkola:

• Abeetabye mu mpaka zino:Omugatte gwa...158 abasajja n’abakazi abalamu abali wakati w’emyaka20 ne 59 emyakabaali bayingiziddwa mu magye. Bannakyewa abalina ebyafaayo by’obujjanjabi eby’amangu oba ebitawona, abo abaanywa ebisukka mu...500 ml za kaawa, caayi, ebyokunywa ebikalu, n’ebyokunywa ebitamiiza buli lunaku, abo aba...yanywa ebyokunywa ebitamiiza ennaku ezisukka mu bbiri mu wiiki, abo abaali bakozesa bulijjo eddagala eriziyiza obuwuka obuleeta obulwadde buno mu biseera eby’emabegaemyezi esatu, abanywa sigala, abo abalina emize egy’okukola dduyiro ennyo, n’abo abatatuukana na mutindo gwa kunywa buli lunaku ogwa 500 - 2500 ml z’amazzi agalongooseddwa baaggyibwamu. Oluvannyuma, abeetabye mu kugezesebwa 41 abalina ebisaanyizo baaweebwa mu ngeri ey’ekifuulannenge mu kibinja ky’amazzi ga haidrojeni (n = 22) n’ekibinja ky’amazzi aga bulijjo (n = 19). Wabula mu nkola y’okunoonyereza, abantu 2 baava mu kibinja ky’amazzi aga haidrojeni ate 1 okuva mu kibinja ky’amazzi aga bulijjo. Mu nkomerero, .20abeetabye mu kibinja ky’amazzi ga haidrojeni ne18mu kibinja ky’amazzi ekya bulijjo baamaliriza okugezesebwa okw’okuyingira mu nsonga okwa wiiki 4.
• Enkola z’okuyingira mu nsonga:Ekibinja ky’amazzi ga haidrojeni ekyakozesebwaLiita 1.5 ez’amazzi agalimu haidrojeni(nga kirimu haidrojeni 0.753 ± 0.012 mg/l) buli lunaku, ate ekibinja ky’amazzi aga bulijjo kyanywa amazzi aga bulijjo ag’enkanankana. Abeetabye mu kutendekebwa kuno baalina okumaliriza amazzi mu ccupa ya 500 ml mu ssaawa emu nga bamaze okugiggulawo. Ng’oggyeeko kaawa, caayi, ebyokunywa ebikalu, n’ebyokunywa ebitamiiza, tewali mazzi malala gonna gakkirizibwa, era omugatte gw’okunywa ebyokunywa bino eby’enjawulo gwafugibwa obutasukka 500 ml buli lunaku.

• Obusobozi bw’okuziyiza obuwuka obuleeta obulwadde n’okwonooneka kw’ekirungo kya Oxidative: Oluvannyuma lwa wiiki nnya, byombi okunywa amazzi aga bulijjo n’amazzi agalimu haidrojeni byavaako okweyongera mu serum biological antioxidant potential (BAP). Mu bantu bonna, tewaaliwo njawulo nnene wakati w’ekibinja ky’amazzi ga haidrojeni n’ekibinja ky’amazzi aga bulijjo mu nsonga za BAP. Wabula, ku beetabye mu kugezesebwa abasukka mu myaka 30, okunywa amazzi ga haidrojeni kyavaamu okweyongera okw’amaanyi mu BAP (p = 0.028). Mu kibinja ekito (< emyaka 30), tewali kikulu kikwata ku mazzi ga haidrojeni ku BAP yalabibwa (p = 0.534).
• Apoptosis of Peripheral Blood Mononuclear Cells (PBMCs) ne Profile y’obutoffaali obuziyiza endwadde mu musaayi:Ku ntandikwa, tewaaliwo njawulo nnene mu mirundi gy’obutoffaali obufa mu musaayi wakati w’ebibinja byombi. Wabula oluvannyuma lw’okugezesebwa kwa wiiki 4, bw’ogeraageranya n’ekibinja ky’amazzi ekya bulijjo, ekitundu kya apoptotic PBMCs mu kibinja ky’amazzi ga haidrojeni kyali wansi nnyo (p = 0.036). Ekirala, okuyita mu kwekenneenya flow cytometry, kyazuulibwa nti emirundi gy’obutoffaali bwa CD14+ mu kibinja ky’amazzi ga haidrojeni gyakendeera.
• Okwekenenya ebiwandiiko ebikwata ku biwandiiko (Transcriptome).:Okwekenenya ensengeka ya RNA eya PBMCs kwalaga nti waliwo enjawulo nnene wakati wa transcriptome y’ekibinja ky’amazzi ga haidrojeni n’eky’ekibinja ky’amazzi aga bulijjo. Okusinga, emikutu gy’okuwandiika egyekuusa ku kuddamu kw’okuzimba n’ekkubo ly’obubonero bwa NF-κB mu kibinja ky’amazzi ga haidrojeni gyali gya wansi nnyo.